Преподаватели и сотрудники

Грошева Вероника Дмитриевна

Занимаемые должности

Доцент (Кафедра биотехнологии)





Сайт https://muctr.ru
Уровень образования Высшее


Преподаваемые дисциплины

Общая биология

Общая микробиология

Учёная степень

Кандидат технических наук

Наименование направления подготовки и (или) специальности


Общий стаж работы 13 лет (с 01.03.2006)
Стаж работы по специальности 1 год (с 01.09.2018)


A quantitative model of bacillus cereus atcc 9634 growth inhibition by bifidobacteria for synbiotic effect evaluation / B. A. Karetkin, E. V. Guseva, S. A. Evdokimova et al. // World Journal of Microbiology and Biotechnology. — 2019. — Vol. 35. — P. 89. The present study is dedicated to the development of novel criteria for assessing the synbiotic effect of prebiotic and probiotic composition against a specific pathogen. These criteria were obtained from the quantitative model of Bifidobacterium adolescentis ATCC 15703 and Bacillus cereus ATCC 9634 (as a model food contaminant) competition in co-culture fermentation. The model is based on the hypothesis that probiotics can reduce the specific growth rate of non-probiotics by producing short-chain fatty acids. To define the relationship between the specific growth rate of non-probiotics and short-chain fatty acid yields, the inhibition constants were determined separately for each inhibitor produced by bifidobacteria (lactic, acetic and propionic acids) in a pure culture of bacilli. Two different equations based on the minimum inhibitor concentration (MIC) and inhibition constant (Ki) were used to connect the specific growth rate and concentrations of inhibitors. The yields of the inhibitors mentioned above were obtained from co-culture experiments. The experimental values and the values predicted by the model of Bacillus count did not differ significantly (R2 not less than 0.83) in the competition experiments. Therefore, the general criterion of the synbiotic effect was derived from the model and presents the coefficient of non-probiotic specific growth rate reduction as a result of probiotic growth and inhibitor formation in the final co-culture fermentation. This criterion has been examined for different commercial prebiotics coupled with the Bifidobacterium adolescentis strain. The synergistic combination of inulin GR with bifidobacteria had the best effect against Bacillus cereus ATCC 9634. [ DOI ]

The study of ph adjustment effect to bacillus cereus atcc 11778 growth inhibited by bifidobacterium metabolites for prebiotic activity assessment / B. A. Karetkin, E. V. Guseva, A. S. Mishchenko et al. // 18th International Multidisciplinary Scientific GeoConference SGEM 2018. — Vol. 18 of Advances in biotechnology. — Albena, Bulgaria, 2018. — P. 653–660.

Algorithm of multi-criterion green process assessment for renewable raw materials bioconversion / A. Makarova, D. Baurin, M. Gordienko et al. // Journal of Cleaner Production. — 2017. — Vol. 162. — P. 380–390. [ DOI ]

Biosynthesis of lactic acid in a membrane bioreactor for cleaner technology of polylactide production / A. Kuznetsov, A. Beloded, A. Derunets et al. // Clean Technologies and Environmental Policy. — 2017. — Vol. 19, no. 3. — P. 869–882.

Enzymatic cereal hydrolysates for cultivation and halobacterium salinarum biomass production / E. D. Murzina, V. D. Grosheva, E. E. Savelyeva et al. // 17th International Multidisciplinary Scientific GeoConference SGEM 2017. — Vol. 17 of Advances in Biotechnology. — Vienna, Austria, 2017. — P. 235–242. [ DOI ]